2,2,2-Trichloroethyl chloroformate, 97%

Description

CAS: 17341-93-4 | C3H2Cl4O2 | 211.847 g/mol

2,2,2-Trichloroethyl chloroformate is used as a protecting reagent for aliphatic and aromatic hydroxyl and amino groups. It is used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples, during N-demethylation of dextromethorphan. It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2,2-Trichloroethyl chloroformate is used as a protecting reagent for aliphatic and aromatic hydroxyl and amino groups. It is used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples, during N-demethylation of dextromethorphan. It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.

Solubility
Soluble in Ether, Benzene, Chloroform, Ethanol. Insoluble in water.

Notes
Moisture Sensitive. Desiccate at 4°C. Store under inert gas. Incompatible materials are Strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 17341-93-4
• Molecular Formula: C3H2Cl4O2
• Molecular Weight (g/mol): 211.847
• MDL Number: MFCD00000810
• InChI Key: LJCZNYWLQZZIOS-UHFFFAOYSA-N
• Synonym: 2,2,2-trichloroethyl chloroformate, trichloroethyl chloroformate, 2,2,2-trichloroethylchloroformate, carbonochloridic acid, 2,2,2-trichloroethyl ester, 2,2,2-trichloroethoxycarbonyl chloride, chloroformic acid 2,2,2-trichloroethyl ester, formic acid, chloro-, 2,2,2-trichloroethyl ester, chloro 2,2,2-trichloroethoxy methanone, beta, beta, beta-trichloroethoxycarbonyl chloride, troc
• PubChem CID: 87063
• IUPAC Name: 2,2,2-trichloroethyl carbonochloridate
• SMILES: C(C(Cl)(Cl)Cl)OC(=O)Cl

• Melting Point: 0°C to 2°C
• Density: 1.539
• Boiling Point: 171°C to 172°C
• Flash Point: >100°C (212°F)
• Refractive Index: 1.47
• Quantity: 25 g
• UN Number: UN3277
• Beilstein: 970619
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in Ether,Benzene,Chloroform,Ethanol. Insoluble in water.
• Formula Weight: 211.86
• Percent Purity: 97%
• Chemical Name or Material: 2,2,2-Trichloroethyl chloroformate

Safety and Handling

Hazard Category	H302-H314-H331-H335
Hazard Statement	GHS H Statement H301-H330-H314-H318 Toxic if swallowed. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: CHLOROFORMATES, TOXIC, CORROSIVE, N.O.S.
EINECSNumber	241-363-7
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only