Medchemexpress LLC 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole | 875787-07-8 | MFCD16495812 | 100.0% | 422.78 g·mol⁻¹ | C21H12ClF5N2 | 50 MG

Supplier:  Medchemexpress LLC HY1062950MG

LXR-623 is a brain-penetrant small-molecule agonist of liver X receptors with potent activity at both LXRα and LXRβ. It is used in preclinical research to modulate cholesterol homeostasis and has demonstrated activity in glioblastoma models. The compound is supplied as a high-purity solid with recommended solvents and storage conditions for in vitro and in vivo studies.

• Brain-penetrant LXRα/β agonist with LXRα IC50 = 24 nM and LXRβ IC50 = 179 nM.
• Molecular formula C21H12ClF5N2 and molecular weight 422.78 g·mol⁻¹.
• High purity (99.95%) suitable for research applications.
• Soluble in DMSO at ≥ 47 mg/mL and formulatable for in vivo dosing at ≥ 2.5 mg/mL in common vehicles.
• Stable as a powder at -20 °C for up to 3 years; store in solvent at -80 °C for long-term storage.
• Available in multiple solid pack sizes, including 50 mg, for laboratory use.

Catalog No. 50-002-44381