2,2-Dimethylbutyryl chloride, 98%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin, the drug, is sold under the trade name Zocor. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic.

Solubility
Reacts with water. Soluble in chloroform and ethyl acetate.

Notes
Moisture sensitive. Store away from water/moisture, strong bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep ignition sources away. Protect from electrostatic charges.

Specifications

Chemical Identifiers

• CAS: 5856-77-9
• Molecular Formula: C6H11ClO
• Molecular Weight (g/mol): 134.60
• MDL Number: MFCD03093071
• InChI Key: LDJUYMIFFNTKOI-UHFFFAOYSA-N
• Synonym: 2,2-dimethylbutyryl chloride, 2,2-dimethyl butyryl chloride, 2,2-dimethyl-butyryl chloride, butanoylchloride, 2,2-dimethyl, 2,2-dimethylbutyric acid chloride, butanoyl chloride, 2,2-dimethyl, 2,2-dimethylbutyrylchloride, acmc-1aznz, ksc274k4n, 2,2-dimethylbutyryl chloride 10g
• PubChem CID: 79958
• IUPAC Name: 2,2-dimethylbutanoyl chloride
• SMILES: CCC(C)(C)C(Cl)=O

• Density: 0.98
• Boiling Point: 133°C
• Flash Point: 29°C (84°F)
• Refractive Index: 1.424
• Quantity: 10 g
• UN Number: UN2920
• Beilstein: 1743935
• Sensitivity: Moisture sensitive
• Solubility Information: Reacts with water. Soluble in chloroform and ethyl acetate.
• Formula Weight: 134.61
• Percent Purity: 98%
• Chemical Name or Material: 2,2-Dimethylbutyryl chloride

Safety and Handling

Hazard Category	H226-H314-H335
Hazard Statement	GHS H Statement H314-H318-H226 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.
EINECSNumber	227-478-5
TSCA	No
Recommended Storage	Ambient temperatures

SDS