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Medchemexpress LLC 2-(2-fluorophenyl)-N-hydroxy-2-[4-[5-(trifluoromethyl)pyrimidin-2-yl]phenyl]acetamide | 1629729-98-1 | 98.1% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11993950MG

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CHDI-390576 is a potent, cell-permeable, CNS-penetrant small-molecule inhibitor selective for class IIa histone deacetylases (HDAC4, HDAC5, HDAC7, HDAC9). It is provided as a high-purity research compound for biochemical and cellular studies of HDAC function and selectivity.

  • Low-nanomolar inhibitory activity against class IIa HDAC isoforms (reported IC50s: HDAC4 54 nM, HDAC5 60 nM, HDAC7 31 nM, HDAC9 50 nM).
  • High selectivity against class I HDACs and over HDAC8 and HDAC6.
  • CNS penetrant and cell permeable for central nervous system research.
  • High purity suitable for biochemical and cellular assays.
  • Molecular formula C19H13F4N3O2; molecular weight 391.32.

Catalog No. 50-002-34654


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