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Medchemexpress LLC 2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile | 118409-58-8 | MFCD00133900 | 99.0% | 202.17 g/mol | C10H6N2O3 | 5 MG
SDP

Catalog No. 5000247987
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Tyrphostin 25 (AG82) is a small-molecule inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase that also acts as a GPR35 agonist. It is commonly used in cell signaling and pharmacology research; reported activities include EGFR inhibition (IC50 ≈ 3 μM in A431 cells) and GPR35 activation (EC50 ≈ 5.3 μM).

  • Selective EGFR tyrosine kinase inhibition for cell signaling and migration studies.
  • GPR35 agonist activity supports investigation of alternative GPCR-mediated pathways.
  • High purity (~99.0%) suitable for biochemical and cellular assays.
  • Solid, yellow-brown material with molecular weight 202.17 and formula C10H6N2O3.
  • Recommended storage: powder at -20°C (stable ~3 years); in solvent store at -80°C for long-term stability.

Catalog No. 50-002-47987 Supplier Medchemexpress LLC Supplier No. HY1019585MG
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Tyrphostin 25 (AG82) is a small-molecule inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase that also acts as a GPR35 agonist. It is commonly used in cell signaling and pharmacology research; reported activities include EGFR inhibition (IC50 ≈ 3 μM in A431 cells) and GPR35 activation (EC50 ≈ 5.3 μM).

  • Selective EGFR tyrosine kinase inhibition for cell signaling and migration studies.
  • GPR35 agonist activity supports investigation of alternative GPCR-mediated pathways.
  • High purity (~99.0%) suitable for biochemical and cellular assays.
  • Solid, yellow-brown material with molecular weight 202.17 and formula C10H6N2O3.
  • Recommended storage: powder at -20°C (stable ~3 years); in solvent store at -80°C for long-term stability.

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