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Sigma Aldrich 2-(3-(But-3-Yn-1-Yl)-3H-Diazirin-3-Yl)Ethan-1-Amine

Catalog No. 900683100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-068-3100MG 25 mL
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.Technology Spotlight: Trifuctional Probe Building BlocksDesign and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome ProfilingMinimalist Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling

Specifications

CAS 554-70-1
Density 0.857 g/mL
Molecular Formula C6H15P
Linear Formula (C2H5)3P
MDL Number MFCD00009256
Quantity 25 mL
Molecular Weight (g/mol) 118.16 g/mol
Biological Activity Central Nervous System
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