Sigma Aldrich 2-(3-But-3-Ynyl-3H-Diazirin-3-Yl)-Ethanol

Catalog No.	Quantity
90-086-350MG	50 mg

Catalog No. 90-086-350MG Supplier Sigma Aldrich Supplier No. 90086350MG

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.Technology Spotlight: Trifunctional Probe Building BlocksFluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone DeacetylasesIn Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L InhibitorsReversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX associationDesign and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

Specifications

• CAS: 653600-56-7
• Molecular Formula: C16H22N4O10
• Linear Formula: C16H22N4O10
• Quantity: 50 mg
• Synonym: Ac4GalNAz
• Molecular Weight (g/mol): 430.37 g/mol