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Apexbio Technology LLC 2,3-Butanedione-2-monoxime 57-71-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC C35645.1
2 3-Butanedione-2-monoxime (BDM CAS 57-71-6) is a small molecule inhibitor of myosin ATPase activity By interfering with the ATP-driven cross-bridge cycling of myosin BDM disrupts the conversion of chemical energy into mechanical force impacting cytoskeletal dynamics In vitro studies have shown that treatment with BDM in fission yeast leads to reduced cell size increased septation and altered actin organization though cytokinetic actin ring formation is maintained BDM is widely employed as a reversible probe of myosin function in muscle and cell biology research to elucidate contractile mechanisms and cytoskeletal behaviors
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