Learn More
Cayman Chemical 2'3'-cGAMP (sodium salt), 1 mg

Supplier: Cayman Chemical 198871
Molecular Formula C20H22N10O13P2 • 2Na, Purity ≥98%, Formula Weight 718.4, Synonyms: adenylyl-(3'→5')-2'-guanylic acid, cyclic nucleotide, disodium salt, Guanosine-Adenosine 2',3'-cyclic monophosphate, 2'-3'-Cyclic GMP-AMP; A second messenger produced from ATP and GTP by cGMP-AMP synthase (cGAS) in the cytoplasm of mammalian cells in response to the presence of DNA; contains a non-canonical 25-phosphodiester bond; binds tightly to the adapter protein STING (Kd = 3.79 nM) and induces IFN- mRNA expression (EC50 = 19.4 nM in L929 cells).
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.