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Cayman Chemical 2'3'-cGAMP (sodium salt), 1 mg

Supplier: Cayman Chemical 198871
Molecular Formula C20H22N10O13P2 • 2Na, Purity ≥98%, Formula Weight 718.4, Synonyms: adenylyl-(3'→5')-2'-guanylic acid, cyclic nucleotide, disodium salt, Guanosine-Adenosine 2',3'-cyclic monophosphate, 2'-3'-Cyclic GMP-AMP; A second messenger produced from ATP and GTP by cGMP-AMP synthase (cGAS) in the cytoplasm of mammalian cells in response to the presence of DNA; contains a non-canonical 25-phosphodiester bond; binds tightly to the adapter protein STING (Kd = 3.79 nM) and induces IFN- mRNA expression (EC50 = 19.4 nM in L929 cells).
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