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Medchemexpress LLC 2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-3-fluoro-1-naphthonitrile hydrochloride | 99.88% | 460.89 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY138684A

Encompass_Preferred

MRTX9768 hydrochloride is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor.

  • Potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor.
  • Inhibits SDMA and cell proliferation in HCT116 MTAP-del cells.
  • Selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma.
  • Demonstrates dose-dependent inhibition of SDMA in MTAP-del tumors in xenograft studies.
  • Exhibits a favorable ADME profile with good bioavailability in mice and dogs.

Catalog No. 50-003-48485


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