2,4,5-Trichloropyrimidine, 98%

Description

CAS: 5750-76-5 | C4HCl3N2 | 183.416 g/mol

2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhibitors.

Solubility
Not miscible or difficult to mix in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 5750-76-5
• Molecular Formula: C4HCl3N2
• Molecular Weight (g/mol): 183.416
• MDL Number: MFCD03788200
• InChI Key: GIKMWFAAEIACRF-UHFFFAOYSA-N
• Synonym: 2,5,6-trichloropyrimidine, 2,4,5-trichloro-pyrimidine, trichloropyrimidine, pyrimidine, 2,4,5-trichloro, 2,4,5-trichlorpyrimidin, pubchem5302, zlchem 1349, pyrimidine, trichloro, acmc-209lys, 2,5-trichloropyrimidine
• PubChem CID: 237259
• IUPAC Name: 2,4,5-trichloropyrimidine
• SMILES: C1=C(C(=NC(=N1)Cl)Cl)Cl

• Density: 1.6
• Boiling Point: 84°C (1 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.573
• Quantity: 5 g
• UN Number: UN1760
• Beilstein: 4449
• Solubility Information: Not miscible or difficult to mix in water.
• Formula Weight: 183.43
• Percent Purity: 98%
• Chemical Name or Material: 2,4,5-Trichloropyrimidine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUIDS, N.O.S.
EINECSNumber	000-000-0
TSCA	No

SDS

RUO – Research Use Only