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Medchemexpress LLC 2-((4-chlorophenyl)amino)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)th | 2785323-62-6 | 99.6% | C29H29ClN6O5S | 10MG
SDP

Catalog No. 5000260140
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PROTAC-O4I2 is a proteolysis-targeting chimera that promotes degradation of the splicing factor SF3B1, leading to apoptosis in K562 cells. It is supplied as a solid and as DMSO solution formats for use in cellular assays and targeted protein degradation research.

  • Targets splicing factor SF3B1 and induces its degradation in cells.
  • Demonstrated cellular activity with FLAG-SF3B1 degradation IC50 ≈ 0.244 μM.
  • Exhibits antiproliferative activity in K562-derived cell lines.
  • High supplied purity (≈99.6%) for biochemical and cellular studies.
  • Available as powder and as 10 mM solution in DMSO for immediate use in assays.

Catalog No. 50-002-60140 Supplier Medchemexpress LLC Supplier No. HY14188110MG
May include imposed supplier surcharges.
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PROTAC-O4I2 is a proteolysis-targeting chimera that promotes degradation of the splicing factor SF3B1, leading to apoptosis in K562 cells. It is supplied as a solid and as DMSO solution formats for use in cellular assays and targeted protein degradation research.

  • Targets splicing factor SF3B1 and induces its degradation in cells.
  • Demonstrated cellular activity with FLAG-SF3B1 degradation IC50 ≈ 0.244 μM.
  • Exhibits antiproliferative activity in K562-derived cell lines.
  • High supplied purity (≈99.6%) for biochemical and cellular studies.
  • Available as powder and as 10 mM solution in DMSO for immediate use in assays.

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