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Apexbio Technology LLC 2,4-Diamino-6-hydroxypyrimidine 56-06-4 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B63145.1
2 4-Diamino-6-hydroxypyrimidine (CAS 56-06-4) is a small molecule inhibitor targeting GTP cyclohydrolase I the rate-limiting enzyme in the de novo biosynthesis of tetrahydrobiopterin (BH4) By suppressing GTP cyclohydrolase I activity this compound reduces intracellular levels of BH4 consequently leading to decreased nitric oxide (NO) synthesis It is commonly utilized in studies investigating the roles of BH4 and NO in physiological and pathological contexts including research on neuronal signaling immune modulation and cardiovascular dysfunction
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