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Medchemexpress LLC 2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine | 221148-46-5 | 99.7% | 5 MG
SDP

Catalog No. 5000233169
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GW-406381 is a highly selective cyclooxygenase-2 (COX-2) inhibitor used as a research reagent in preclinical pharmacology and pain models. It attenuates spontaneous ectopic discharge in sural nerves following chronic constriction injury in rats and is provided as a high-purity solid for laboratory use.

  • Selective COX-2 inhibitor.
  • Used in preclinical pain and neurobiology studies.
  • High purity (≈99.7%).
  • Molecular weight 393.46 g/mol.
  • Chemical formula C21H19N3O3S.
  • Soluble in DMSO (100 mg/mL); in vivo formulations reported with ≥2.5 mg/mL solubility.
  • Powder storage: -20°C for long-term stability.
  • Recommended DMSO stock concentrations: 1 mM, 5 mM, and 10 mM (mass-to-volume guidance available).

Catalog No. 50-002-33169 Supplier Medchemexpress LLC Supplier No. HY1193045MG
May include imposed supplier surcharges.
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GW-406381 is a highly selective cyclooxygenase-2 (COX-2) inhibitor used as a research reagent in preclinical pharmacology and pain models. It attenuates spontaneous ectopic discharge in sural nerves following chronic constriction injury in rats and is provided as a high-purity solid for laboratory use.

  • Selective COX-2 inhibitor.
  • Used in preclinical pain and neurobiology studies.
  • High purity (≈99.7%).
  • Molecular weight 393.46 g/mol.
  • Chemical formula C21H19N3O3S.
  • Soluble in DMSO (100 mg/mL); in vivo formulations reported with ≥2.5 mg/mL solubility.
  • Powder storage: -20°C for long-term stability.
  • Recommended DMSO stock concentrations: 1 mM, 5 mM, and 10 mM (mass-to-volume guidance available).

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