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Sigma Aldrich 2,5-Dibromohexanediamide

Catalog No. 900607250MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-060-7250MG 250 mg
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

This compound has been shown to be a useful reagent for the conversion of cysteine to dehydroalanine (DHA) in peptides or proteins. This enables chemical mutagenesis in which DHA can be efficiently reacted with iodide building blocks to add various natural and unnatural side chains on proteins. It was also shown that other modifications could be added through DHA such as phosphorylation, methylation, and glycosylation. In other research it was shown that DHA can be used to make ubiquitin conjugates that have a bond that mimics the native isopeptide bond.

Specifications

CAS 42969-65-3
Density 0.89 g/mL at 25°C
Boiling Point 108°C to 111°C
Molecular Formula C4H6O
Linear Formula HC///CCH(OH)CH3
Quantity 250 mg
MDL Number MFCD00211237
Molecular Weight (g/mol) 70.09 g/mol
Biological Activity Respiratory System
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