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Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 1-(4-(tetrazin-3-yl)phenyl)-3,19-dioxo-PEG4-SS-oate | 95.0% | 723.82 | C30H41N7O10S2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY13604010MG

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Tetrazine-PEG4-SS-NHS is a cleavable PEG4-based heterobifunctional linker containing a tetrazine reactive group, an NHS ester for amine coupling, and a disulfide cleavable bond for release. It is designed for bioconjugation and antibody-drug conjugate synthesis, enabling rapid click conjugation and controlled intracellular release.

  • Cleavable disulfide linkage for intracellular release.
  • Tetrazine group enables rapid iEDDA click conjugation with trans-cyclooctene reagents.
  • NHS ester enables efficient coupling to primary amines.
  • PEG4 spacer improves solubility and reduces steric hindrance.
  • Available in small milligram quantities for research use.

Catalog No. 50-002-03130


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