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Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]... | 1802907-92-1 | MFCD28334559 | 97.0% | C24H31N5O9 | 10MG

Supplier: Medchemexpress LLC HY14126910MG
Methyltetrazine-PEG5-NHS ester is a PEG5-based linker bearing a methyltetrazine group and an N-hydroxysuccinimide (NHS) ester. It enables rapid bioorthogonal labeling via inverse-electron-demand Diels-Alder reactions with trans-cyclooctene derivatives and provides an activated ester for amine coupling; the PEG5 spacer improves aqueous solubility and spacing in conjugates. Molecular formula C24H31N5O9, MW 533.53 g·mol⁻¹.
- Enables fast bioorthogonal conjugation via inverse-electron-demand Diels-Alder.
- Provides an activated NHS ester for efficient amine coupling.
- Peg5 spacer increases solubility and reduces steric hindrance.
- Suitable for synthesis of linkers, bioconjugates, and PROTACs.
- Supplied at high purity for research applications.
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