Medchemexpress LLC 2-(5-Phenyl-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-N-(5-phenylpyridin-2-yl)acetamide | 2074607-48-8 | 99.8% | 432.48 g·mol⁻1 | C26H20N6O | 25 MG

Supplier:  Medchemexpress LLC HY10085325MG

A potent small-molecule Porcn inhibitor for research use that blocks Wnt protein secretion and downstream signaling. It exhibits an EC50 of 80 pM in L-Wnt-STF cells and suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays. Supplied as a high-purity solid or as a 10 mM solution in DMSO for experimental convenience.

• Potent Porcn inhibition with an EC50 of 80 pM in L-Wnt-STF cells.
• Blocks secretion of Wnt proteins and downstream signaling pathways.
• Suppresses phosphorylation of Dvl2/3 and LRP6 in cell-based assays.
• High purity (≈99.8%) suitable for biochemical and cellular studies.
• Available as solid quantities (including 25 mg) and as a 10 mM solution in DMSO.
• Recommended storage: solid at 4°C; in solvent at -80°C for long-term stability.

Catalog No. 50-002-12218