2(5H)-Furanone, 96%

Description

CAS: 497-23-4 | C4H4O2 | 84.07 g/mol

2(5H)-Furanone is employed in the preparation of 5-substituted 2(5H) furanones (gamma-butenolides) catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts through direct aldol reaction with aromatic aldehydes. Further, it is used in the synthesis of lignans by Michael addition reactions. In addition to this, it is used in three-component Michael-Aldol reactions with an aldehyde and thiolate or carbanion.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2(5H)-Furanone is employed in the preparation of 5-substituted 2(5H) furanones (gamma-butenolides) catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts through direct aldol reaction with aromatic aldehydes. Further, it is used in the synthesis of lignans by Michael addition reactions. In addition to this, it is used in three-component Michael-Aldol reactions with an aldehyde and thiolate or carbanion.

Solubility
Immiscible with water.

Notes
Light and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 497-23-4
• Molecular Formula: C4H4O2
• Molecular Weight (g/mol): 84.07
• MDL Number: MFCD00005376
• InChI Key: VIHAEDVKXSOUAT-UHFFFAOYSA-N
• Synonym: 2 5h-furanone, furan-2 5h-one, butenolide, 2-butenolide, gamma-crotonolactone, 2-buten-4-olide, isocrotonolactone, 2-oxo-2,5-dihydrofuran, crotonolactone, 2-5h-furanone
• PubChem CID: 10341
• ChEBI: CHEBI:38118
• IUPAC Name: 2H-furan-5-one
• SMILES: O=C1OCC=C1

• Melting Point: 3°C to 4°C
• Density: 1.197
• Boiling Point: 212°C to 214°C
• Flash Point: 101°C (213°F)
• Refractive Index: 1.469
• Quantity: 25 g
• Beilstein: 383585
• Sensitivity: Light sensitive
• Solubility Information: Immiscible with water.
• Formula Weight: 84.07
• Percent Purity: 98%
• Chemical Name or Material: 2(5H)-Furanone

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	207-839-3
RTECSNumber	LU3453000
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only