2,6-Di-tert-butyl-4-methylpyridine, 97%

Catalog No.	Quantity
AAL1414303	1 g
AAL1414306	5 g

Catalog No. AAL1414303 Supplier Thermo Scientific Chemicals Supplier No. L1414303

Description

CAS: 38222-83-2 | C14H23N | 205.35 g/mol

2,6-Di-tert-butyl-4-methylpyridine is used for the generation of enol triflates from ketones using trifluoromethanesulfonic anhydride. It is also used in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives, as base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives and in diastereoselective synthesis of β-thiomannopyranosides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,6-Di-tert-butyl-4-methylpyridine is used for the generation of enol triflates from ketones using trifluoromethanesulfonic anhydride. It is also used in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives, as base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives and in diastereoselective synthesis of β-thiomannopyranosides.

Solubility
Sparingly soluble in water. Soluble in ethanol, acetic acid and diethyl ether.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2 - 8°C. Store under inert gas. It is sensitive to air and light.

Specifications

Chemical Identifiers

• CAS: 38222-83-2
• Molecular Formula: C14H23N
• Molecular Weight (g/mol): 205.35
• MDL Number: MFCD00006305
• InChI Key: HVHZEKKZMFRULH-UHFFFAOYSA-N
• Synonym: 2,6-di-tert-butyl-4-methylpyridine, dtbmp, pyridine, 2,6-bis 1,1-dimethylethyl-4-methyl, 2,6-di-t-butyl-4-methylpyridine, 2,6-ditert-butyl-4-methyl-pyridine, 2,6-bis tert-butyl-4-methylpyridine, pubchem10244, acmc-209iyr, ksc490s2n, 2,6-di-t-butyl 4-methylpyridine
• PubChem CID: 98898
• SMILES: CC1=CC(=NC(=C1)C(C)(C)C)C(C)(C)C

• Melting Point: 30°C to 35°C
• Boiling Point: 232°C to 234°C
• Flash Point: 83°C (181°F)
• Refractive Index: 1.4765
• Quantity: 1 g
• Beilstein: 130503
• Sensitivity: Air and light sensitive
• Solubility Information: Sparingly soluble in water. Soluble in ethanol,acetic acid and diethyl ether.
• IUPAC Name: 2,6-ditert-butyl-4-methylpyridine
• Formula Weight: 205.35
• Percent Purity: 97%
• Chemical Name or Material: 2,6-Di-tert-butyl-4-methylpyridine

Safety and Handling

Hazard Category	H228-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Hazard Class: 4.1; Packaging Group: II
EINECSNumber	253-834-4
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only