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2,6-Di-tert-butyl-4-methylpyridine, 97%
Description
2,6-Di-tert-butyl-4-methylpyridine is used for the generation of enol triflates from ketones using trifluoromethanesulfonic anhydride. It is also used in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives, as base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives and in diastereoselective synthesis of β-thiomannopyranosides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
2,6-Di-tert-butyl-4-methylpyridine is used for the generation of enol triflates from ketones using trifluoromethanesulfonic anhydride. It is also used in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives, as base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives and in diastereoselective synthesis of β-thiomannopyranosides.
Solubility
Sparingly soluble in water. Soluble in ethanol, acetic acid and diethyl ether.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2 - 8°C. Store under inert gas. It is sensitive to air and light.

Specifications
Specifications
Melting Point | 30°C to 35°C |
Boiling Point | 232°C to 234°C |
Flash Point | 83°C (181°F) |
Refractive Index | 1.4765 |
Quantity | 5 g |
Beilstein | 130503 |
Sensitivity | Air and light sensitive |
Solubility Information | Sparingly soluble in water. Soluble in ethanol,acetic acid and diethyl ether. |
IUPAC Name | 2,6-di-tert-butyl-4-methylpyridine |
Formula Weight | 205.35 |
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Safety and Handling
Hazard Category | H228-H315-H319-H335 |
Hazard Statement | GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
Precautionary Statement | P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c |
DOTInformation | Hazard Class: 4.1; Packaging Group: II |
EINECSNumber | 253-834-4 |
TSCA | No |
Recommended Storage | Keep cold; Store under Nitrogen |
RUO – Research Use Only
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