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Cayman Chemical 2 6-DIchloropurIn-9D-rIbo 25mg
SDP

Supplier:  Cayman Chemical 3140525 MG

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A multi-kinase inhibitor inhibits BTK LCK and LYN (Kis 8 2 4 6 and 2 5 nM respectively) as well as the activity of three receptor tyrosine kinases and seven non-receptor tyrosine kinases by greater than 90 in a panel of over 100 kinases at 10 UM inhibits calcium flux in Ramos B cells and phosphorylation of PLC 1 (IC50s 0 53 and 0 33 UM respectively) cytotoxic to S1-MI-80 H460/MX20 and KBv200 cancer cells overexpressing the ATP-binding cassette transporter (IC50s 7 8 6 3 and 6 02 UM respectively) in combination with topotecan reduces tumor growth in an H460/MX20 mouse xenograft model at 20 mg/kg

Catalog No. 50-299-0953


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