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Medchemexpress LLC 2,6-Piperidinedione, 3-[4-(4-methoxy-3-thienyl)-1H-1,2,3-triazol-1-yl]- | 2367619-87-0 | 99.8% | C12H12N4O3S | 25 MG

Supplier: Medchemexpress LLC 25MGHY145319
FPFT-2216 is a "molecular glue" compound that degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). It can be used for the research of cancer and inflammatory disease.
- Degrades phosphodiesterase 6D (PDE6D)
- Degrades zinc finger transcription factors Ikaros (IKZF1)
- Degrades Aiolos (IKZF3)
- Degrades casein kinase 1α (CK1α)
- Suitable for cancer research
- Suitable for inflammatory disease research
- Exhibits in vitro activity in MOLT4 cells
- Up-regulates IL-2 production in naive CD4+ T cells
- Induces significant degradation of CK-1α and IKZF1 in CRBNI391V mice
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