2-Amino-4-methylpyridine, 98%

Description

CAS: 695-34-1 | C6H8N2 | 108.144 g/mol

2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methyl­pyridinium 2-hy­droxy­benzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methyl­pyridinium 2-hy­droxy­benzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.

Solubility
Soluble in water (41 mg/ml at 20°C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.

Notes
Hygroscopic. Incompatible with oxidizing agents and moisture. Store under dry inert gas. Protect from humidity and water. Store at -20°C.

Specifications

Chemical Identifiers

• CAS: 695-34-1
• Molecular Formula: C6H8N2
• Molecular Weight (g/mol): 108.144
• MDL Number: MFCD00006321
• InChI Key: ORLGLBZRQYOWNA-UHFFFAOYSA-N
• Synonym: 2-amino-4-methylpyridine, 2-amino-4-picoline, 2-pyridinamine, 4-methyl, ascensil, 4-methyl-2-pyridinamine, 4-methyl-2-pyridylamine, 4-methyl-2-aminopyridine, 4-picoline, 2-amino, w 45 raschig, aminton
• PubChem CID: 1533
• IUPAC Name: 4-methylpyridin-2-amine
• SMILES: CC1=CC(=NC=C1)N

• Melting Point: 97°C to 101°C
• Boiling Point: 231°C
• Flash Point: 118°C (244°F)
• Odor: Unpleasant
• Quantity: 25 g
• UN Number: UN2811
• Beilstein: 107066
• Sensitivity: Hygroscopic
• Merck Index: 14,466
• Solubility Information: Soluble in water (41mg/ml at 20°C),lower alcohols (slightly),chloroform,ethyl acetate,and DMF.
• Formula Weight: 108.14
• Percent Purity: 98%
• Chemical Name or Material: 2-Amino-4-methylpyridine

Safety and Handling

Hazard Category	H301+H311-H315-H319-H335
Hazard Statement	GHS H Statement H301-H311-H318-H315-H335 Toxic if swallowed. Toxic in contact with skin. Causes serious eye damage. Causes skin irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	211-780-9
RTECSNumber	TJ5150000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only