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Cayman Chemical 2-AmInopurInhydrochlorIde 50mg

Supplier: Cayman Chemical 1860950 MG

An orally active Ras inhibitor with selectivity for H-Ras (Ki 46 M) inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 ~1.5 M) exhibits antitumor activity in mice bearing a xenograft of human colon cancer SW480 cells expressing K-RasG12V at an oral dose of 80 mg/kg
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