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Medchemexpress LLC 2'-Azido-2'-deoxycytidine | 51034-68-5 | C9H12N6O4 | 100 MG

Supplier: Medchemexpress LLC HY152448100MG
2'-Azido-2'-deoxycytidine is a purine nucleoside analogue with broad antitumor activity, especially against indolent lymphoid malignancies, acting by inhibiting DNA synthesis and inducing apoptosis. It serves as a click chemistry reagent, possessing an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. Diphosphorylation is required for its function as a nucleotide reductase inhibitor.
- Purine nucleoside analogue with antitumor activity
- Inhibits DNA synthesis and induces apoptosis
- Click chemistry reagent for CuAAc and SPAAC reactions
- Requires diphosphorylation to inhibit nucleotide reductase
- Useful in oligonucleotide and nucleoside analog research
- Applicable in cancer studies, including leukemia
- Relevant for cell cycle and DNA damage investigations
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