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Medchemexpress LLC 2'-Azido-2'-deoxycytidine | 51034-68-5 | C9H12N6O4 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY152448100MG

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2'-Azido-2'-deoxycytidine is a purine nucleoside analogue with broad antitumor activity, especially against indolent lymphoid malignancies, acting by inhibiting DNA synthesis and inducing apoptosis. It serves as a click chemistry reagent, possessing an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. Diphosphorylation is required for its function as a nucleotide reductase inhibitor.

  • Purine nucleoside analogue with antitumor activity
  • Inhibits DNA synthesis and induces apoptosis
  • Click chemistry reagent for CuAAc and SPAAC reactions
  • Requires diphosphorylation to inhibit nucleotide reductase
  • Useful in oligonucleotide and nucleoside analog research
  • Applicable in cancer studies, including leukemia
  • Relevant for cell cycle and DNA damage investigations

Catalog No. 50-003-73387


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