2-Bromo-5-fluorobenzyl bromide, 97%

Description

CAS: 112399-50-5 | C7H5Br2F | 267.923 g/mol

It is an important pharmaceutical intermediate. Alkylation of the β-amino ester 1a with 2-bromo-5-fluorobenzyl bromide yields Benzazepines as a white solid after silica gel chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is an important pharmaceutical intermediate. Alkylation of the β-amino ester 1a with 2-bromo-5-fluorobenzyl bromide yields Benzazepines as a white solid after silica gel chromatography.

Solubility
Difficult to mix in water.

Notes
Store in cool dry condition. Incompatible with strong oxidizing agents. Ensure ventilation. Protect from electrostatic charges.

Specifications

Chemical Identifiers

• CAS: 112399-50-5
• Molecular Formula: C7H5Br2F
• Molecular Weight (g/mol): 267.923
• MDL Number: MFCD00042187
• InChI Key: CZLWYKAZAVYQIK-UHFFFAOYSA-N
• Synonym: 2-bromo-5-fluorobenzyl bromide, 1-bromo-2-bromomethyl-4-fluorobenzene, 5-fluoro-2-bromobenzyl bromide, 2-bromo-5-fluorobenzylbromide, benzene, 1-bromo-2-bromomethyl-4-fluoro, alpha,2-dibromo-5-fluorotoluene, pubchem1953, acmc-1bt22, ksc493i2h, 2-bromo-5-fluoro benzyl bromide
• PubChem CID: 517972
• IUPAC Name: 1-bromo-2-(bromomethyl)-4-fluorobenzene
• SMILES: C1=CC(=C(C=C1F)CBr)Br

• Melting Point: 33°C to 36°C
• Boiling Point: 89°C to 90°C (1 mmHg)
• Refractive Index: 1.59
• Quantity: 5 g
• UN Number: UN3265
• Beilstein: 4177658
• Solubility Information: Difficult to mix in water.
• Formula Weight: 267.92
• Percent Purity: 97%
• Chemical Name or Material: 2-Bromo-5-fluorobenzyl bromide

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only