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Medchemexpress LLC 2-Butanone, 4-[4-(β-D-glucopyranosyloxy)phenyl]- | 38963-94-9 | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHYN6069

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Raspberry ketone glucoside is a melanogenesis inhibitor. It inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway, inhibiting the transcriptional activity of MITFa, and its downstream expression levels of the TYR and TYRP1a genes. It demonstrates significant whitening activity both in vitro (on B16F10 cells) and in vivo (in a zebrafish model).

  • Inhibits melanogenesis through the IL6/JAK1/STAT3 pathway.
  • Reduces transcriptional activity of MITFa and expression levels of TYR and TYRP1a genes.
  • Shows remarkable whitening activity on B16F10 cells in vitro.
  • Reduces internal melanin content and tyrosinase activity in a zebrafish model in vivo.
  • Up-regulates mRNA levels of GP130, IL6ST, JAK1, STAT3, and SOCS3b.
  • Activates macrophages in zebrafish embryos without affecting embryonic melanogenesis.

Catalog No. 50-004-21922


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