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Medchemexpress LLC 2-Buten-1-amine, 3-fluoro-4-(phenylsulfonyl)-, hydrochloride (1:1), (2Z)- | 2409964-40-3 | C10H13ClFNO2S | 25 MG

Supplier: Medchemexpress LLC 25MGHY151498A
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor, abolishing lysyl oxidase activity. It inhibits LOX with IC50s ranging from 0.2 μM to 3.2 μM across various LOX isoforms, and also reduces deposition and crosslinking of collagen I secreted by human fibroblasts.
- Purity of 99.71%
- Solid, white to off-white appearance
- Molecular weight of 265.73
- Storage conditions: 4°C sealed for solid; -80°C for 6 months or -20°C for 1 month in solvent
- Soluble in DMSO at 100 mg/mL
- Inhibits LOX isoforms including Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4
- Reduces collagen I deposition and crosslinking
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