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Medchemexpress LLC 2-chloro-1-[2-[3-(trifluoromethyl)anilino]phenyl]ethanone | 2378626-29-8 | 99.0% | 313.70 g/mol | C15H11ClF3NO | 10MG
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Supplier:  Medchemexpress LLC HY12526910MG

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TED-347 is a potent, irreversible, covalent, allosteric small-molecule inhibitor of the YAP-TEAD protein-protein interaction that blocks TEAD transcriptional activity and has demonstrated antitumor activity in reported assays.

  • Irreversible covalent inhibitor of YAP-TEAD interaction (EC50 = 5.9 μM for TEAD4*Yap1).
  • Covalently binds Cys-367 in TEAD4 (Ki = 10.3 μM).
  • Molecular formula C15H11ClF3NO; molecular weight 313.70 g/mol.
  • CAS number 2378626-29-8.
  • High purity (98.97%).
  • Appearance: light yellow to green yellow solid.
  • Storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (2 years) or -20 °C (1 year).

Catalog No. 50-002-36628


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