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Medchemexpress LLC 2-chloro-1-(2-((3-(trifluoromethyl)phenyl)amino)phenyl)ethanone | 2378626-29-8 | MFCD32689460 | 99.0% | 313.70 g/mol | C15H11ClF3NO | 50MG
SDP

Supplier:  Medchemexpress LLC HY12526950MG

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TED-347 is an irreversible, covalent, allosteric inhibitor of the YAP-TEAD protein-protein interaction that selectively modifies Cys-367 in TEAD4. It has an EC50 of 5.9 μM (TEAD4·Yap1), blocks TEAD transcriptional activity, and has demonstrated antiproliferative activity in cell-based cancer models. For research use only.

  • Potent, irreversible covalent inhibitor of YAP-TEAD interaction.
  • Blocks TEAD transcriptional activity in biochemical and cellular assays.
  • Demonstrated antiproliferative effects in glioblastoma cell studies.
  • High purity (~99.0%) suitable for biochemical and cellular research.
  • Soluble in DMSO and characterized for common in vivo formulations.
  • Stable when stored as powder at recommended cold temperatures.
  • Available in milligram pack sizes including 50 mg and as solution formats.

Catalog No. 50-002-37392


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