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Medchemexpress LLC [2-chloro-3-(trifluoromethyl)phenyl]-[(4R)-1-(5-fluoropyrimidin-2-yl)-4-methyl-6,7-dihydro-4H-triazolo... | 1627902-21-9 | MFCD31556312 | 99.3% | 440.78 g/mol | C18H13ClF4N6O | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11750810MG

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JNJ-54175446 is a brain-penetrant, selective purine P2X7 receptor antagonist used in central nervous system research and clinical investigations of neuroinflammation and mood disorders. It is characterized by high potency at human and rat P2X7 receptors and is available in both solid and solution formats across multiple package sizes.

  • Brain-penetrant P2X7 receptor antagonist.
  • High potency: pIC50 8.46 (human), 8.81 (rat).
  • Available as solid and DMSO solution; multiple package sizes from 1 mg to 500 mg.
  • High reported purity of 99.3%.
  • Suitable for in vitro and in vivo CNS pharmacology studies.

Catalog No. 50-002-27025


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