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Medchemexpress LLC 2-chloro-4-[(3S)-8-[4-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-5,7-dihydropyrrolo... | 2632305-36-1 | 99.4% | 788.33 | C44H46ClN7O5 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15611110MG

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ARD-1676 is an orally active androgen receptor (AR) proteolysis-targeting chimera (PROTAC) that links an AR ligand to a cereblon ligand to induce targeted degradation of AR. It shows potent AR-degrading activity in vitro and in vivo and suppresses tumor growth in AR-driven VCaP xenograft models.

  • Orally active PROTAC degrader targeting the androgen receptor.
  • Demonstrated AR degradation in vitro and efficacy in vivo.
  • High reported purity (~99.36%).
  • Molecular weight approximately 788.33 Da.
  • Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
  • Storage recommendations: refrigerated; in solvent, -80°C (6 months) or -20°C (1 month), protect from light.

Catalog No. 50-002-87750


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