2-(Chloromethoxy)ethyltrimethylsilane, tech. 90%, stab. with 0.1% N,N-Diisopropylethylamine

Catalog No.	Quantity
AAH5507414	25 g
AAH5507403	1 g
AAH5507406	5 g

Catalog No. AAH5507414 Supplier Thermo Scientific Chemicals Supplier No. H5507414

Description

CAS: 76513-69-4 | C6H15ClOSi | 166.72 g/mol

2-(Chloromethoxy)ethyltrimethylsilane is used in the preparation of SEM [2-(trimethylsilyl)ethoxy]methyl]-ethers. It serves as a phenol protecting group in the synthesis of laterifluorones. Further, it reacts with 1H-imidazole to prepare 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(Chloromethoxy)ethyltrimethylsilane is used in the preparation of SEM [2-(trimethylsilyl)ethoxy]methyl]-ethers. It serves as a phenol protecting group in the synthesis of laterifluorones. Further, it reacts with 1H-imidazole to prepare 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 76513-69-4
• Molecular Formula: C6H15ClOSi
• Molecular Weight (g/mol): 166.72
• MDL Number: MFCD00009919
• InChI Key: BPXKZEMBEZGUAH-UHFFFAOYSA-N
• Synonym: 2-trimethylsilyl ethoxymethyl chloride, 2-chloromethoxy ethyl trimethylsilane, sem-chloride, 2-trimethylsilyl ethoxymethylchloride, sem-cl, 2-chloromethyl 2-trimethylsilyl ethyl ether, semcl, 2-chloromethoxy ethyl-trimethylsilane, 2-trimethysilyl-ethoxymethyl chloride
• PubChem CID: 2724271
• IUPAC Name: 2-(chloromethoxy)ethyl-trimethylsilane
• SMILES: C[Si](C)(C)CCOCCl

• Boiling Point: 170°C to 172°C
• Quantity: 25 g
• Linear Formula: (CH₃)₃SiCH₂CH₂OCH₂Cl
• UN Number: UN2920
• Beilstein: 3587289
• Flash Point: 46°C (115°F)
• Formula Weight: 166.72
• Percent Purity: 90%
• Grade: Technical
• Refractive Index: 1.435
• Sensitivity: Moisture sensitive
• Density: 0.942
• Chemical Name or Material: 2-(Chloromethoxy)ethyltrimethylsilane, stabilized with 0.3% N-ethyldiisopropylamine

Safety and Handling

Hazard Category	H226-H314-H335
Hazard Statement	GHS H Statement H314-H318-H226 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.
EINECSNumber	278-483-4
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only