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  6. Sigma Aldrich 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite 

Sigma Aldrich 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

Catalog No. 3023095G Shop All MilliporeSigma Sigma Organic Chemistry Products
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250 mg
5 g
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30-230-95G 5 g
30-230-9250MG 250 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

  • 2-cyanoethyl n,n-diisopropylchlorophosphoramidite was employed:
  • For selective monophosphorylation of carbohydrates and nucleosides
  • For conversion of protected ribonucleosides to phosphoramidites
  • As phosphitylating reagent for 3α-hydroxyl groups in the synthesis of oligodeoxyribonucleotides
  • In a scalable, solution-phase oligonucleotide synthesis employing phosphoramidite chemistry and dmt-, ibu- and bz-protected monomers. intermediates were isolated by extraction without further purification

Specifications

CAS 89992-70-1
Density 1.061 g/mL (at 25°C (literature))
Molecular Formula C9H18ClN2OP
Linear Formula [(CH3)2 CH]2 NP(Cl)OCH2CH2CN
MDL Number MFCD00011544
Quantity 5 g
Synonym Chloro(diisopropylamino)-beta-cyanoethoxyphosphine
Molecular Weight (g/mol) 236.68
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