Sigma Aldrich 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

Catalog No.	Quantity
30-599-55G	5 g
30-599-51G	1 g

Catalog No. 30-599-55G Supplier Sigma Aldrich Supplier No. 3059955G

Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

• 2-cyanoethyl n,n,nα,nα-tetraisopropylphosphordiamidite was used:
• In preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide
• As phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine
• In situ preparation of deoxyribonucleoside phosphoramidites
• In preparation of 2α-deoxy-2α-fluoro-3α-o-(α-cyanoethyl-n,n-diisopropylphosphoramidic)-5α-o-(4-methoxytrityl)-4α-thio-α-d-arabinouridine and 1-(3-o-(α-cyanoethyl-n,n-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-o-(4,4α-dimethoxytrityl)-4-thio-α-d-arabinofuranosyl)-thymine
• As reagent for synthesizing phosphitylated nucleotides

Specifications

• CAS: 102691-36-1
• Density: 0.949 g/mL (at 25°C (literature))
• Boiling Point: 100°C (0.5 mmHg)
• Molecular Formula: C15H32N3OP
• Refractive Index: n20/D 1.470 (literature)
• Linear Formula: {[(CH3)2 CH]2 N}2 POCH2CH2CN
• MDL Number: MFCD00012213
• Quantity: 5 g
• Synonym: Bis(diisopropylamino)(2-cyanoethoxy)phosphine
• Molecular Weight (g/mol): 301.41
• Percent Purity: 97%