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Cayman Chemical 2 cyclohexylmethylPLMbagI 10mg
Supplier: Cayman Chemical 3914310 MG
A derivative of plumbagin; selectively cytotoxic to PANC-1 cells in nutrient-deprived medium over PANC-1 cells in DMEM (PC50s = 0.11 and 47.2 µM, respectively); induces apoptosis in PANC-1 cells at 1 µM; selectively reduces Akt and mTOR phosphorylation in PANC-1 cells under nutrient-deprived, but not nutrient-rich, conditions; tumor volume and weight in a MiaPaCa-2 mouse xenograft model at 50 and 250 UG/animal five times per week
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