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Medchemexpress LLC 2'-Deoxyguanosine 5'-monophosphate disodium hydrate | 146877-98-7 | 99.0% | C10H14N5O7.H2O.2Na | 100 MG
SDP

Supplier:  Medchemexpress LLC HY145538100MG

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2'-Deoxyguanosine 5'-monophosphate disodium hydrate (dGMP) is an oxidizable target of the photosensitizer pterin. It can be used to evaluate the photosensitizing properties of biopterins. Pterin causes a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage. This process involves two main mechanisms in vitro for the photosensitive oxidation of purine nucleotides by pterin.

  • A hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism).
  • Interaction between dGMP and pterin produces singlet molecular oxygen (1O2) (type II mechanism).

Catalog No. 50-003-54139


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