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Medchemexpress LLC 2'-Deoxyuridine (standard) | 951-78-0 | 99.2% | 5 MG
Supplier: Medchemexpress LLC HYD0186R5MG
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine, intended for research and analytical applications. It is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, making it promising for Alzheimer's disease (AD) research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Passes the blood-brain barrier (BBB) in mice.
- Improves cognition and memory loss and attenuates hippocampal damage in Aβ25-35-induced mice models.
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