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Sigma Aldrich 2-(Diphenylphosphanyl)Benzamide

Catalog No. 914487250MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-448-7250MG 5 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

It is recommended to make fresh stock stolutions prior to each use.2-(Diphenylphosphanyl)benzamide (DPBM) is a phosphine useful in the Staudinger reduction in chemical biology and medicinal chemistry. Recently, DPBM was demonstrated to faciliate the reactivation of CRISPR/Cas9 functions by removing azidomethylnicotinyl (AMN) groups used to masked gRNA and inhibit CRISPR systems. AMN groups were originally added with the use of RNA probe NAI-N3 (cat# 913812).Conditional control of RNA-guided nucleic acid cleavage and gene editingSmall-molecule control of protein function through Staudinger reductionA FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues

Specifications

CAS 384184-40-9
Molecular Formula C50H65ClN4O12
Linear Formula C50H65ClN4O12
Quantity 5 mg
Molecular Weight (g/mol) 949.52 g/mol
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