2-Fluoro-5-nitrobenzoic acid, 98%

Description

CAS: 7304-32-7 | C7H4FNO4 | 185.11 g/mol

2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (SNAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support, synthesis of substituted dibenzazocines on solid support, via SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols, in the synthesis of oxazepines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (SNAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support, synthesis of substituted dibenzazocines on solid support, via SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols, in the synthesis of oxazepines.

Solubility
Soluble in chloroform, ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 7304-32-7
• Molecular Formula: C7H4FNO4
• Molecular Weight (g/mol): 185.11
• MDL Number: MFCD00134238
• InChI Key: ICXSHFWYCHJILC-UHFFFAOYSA-N
• Synonym: 2-fluoro-5-nitrobenzoic acid, 2-fluoro-5-nitrobenzoicacid, 2-fluoro-5-nitro-benzoic acid, benzoic acid, 2-fluoro-5-nitro, 2-fluoro-5-nitro-benzoicacid, pubchem1307, acmc-209op6, ksc377e3h, 2-fluoro-5-nitrobenzotc acid, 2-fluoro-5-nitro benzoic acid
• PubChem CID: 280997
• IUPAC Name: 2-fluoro-5-nitrobenzoic acid
• SMILES: OC(=O)C1=CC(=CC=C1F)[N+]([O-])=O

• Melting Point: 142°C to 144°C
• Quantity: 25 g
• Beilstein: 1912835
• Solubility Information: Soluble in chloroform,ethanol.
• Formula Weight: 185.11
• Percent Purity: 98%
• Chemical Name or Material: 2-Fluoro-5-nitrobenzoic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	000-000-0
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only