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Medchemexpress LLC 2-Furancarboxamide, 5-nitro-N-[4-[7-(1,2,3,6-tetrahydro-4-pyridinyl)imidazo[1,2-a]pyridin-3-yl]phenyl] | C25H20F3N5O6 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY153190A5MG

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W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. It inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU, and regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.

  • Potent STAT3 inhibitor
  • Induces ferroptosis
  • Inhibits cancer progression in gastric cancer models
  • Alleviates cancer cell chemoresistance to 5-FU
  • Regulates cell cycle and DNA damage response
  • Regulates oxidative phosphorylation
  • Regulates IL6-JAK-STAT3 pathway
  • Regulates ferroptosis pathway

Catalog No. 50-003-72536


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