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Medchemexpress LLC 2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-me... | 1542132-88-6 | 100.0% | 528.60 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY193595MG

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Vilagletistat (ZED-1227) is a specific and orally active transglutaminase 2 (TG2) inhibitor, with an IC50 of 45 nM. It effectively blocks inflammation-induced TG2 expression and activity, making it suitable for research into celiac disease (CeD).

  • Specific and orally active TG2 inhibitor
  • IC50 of 45 nM against TG2
  • Blocks inflammation-induced TG2 expression and activity
  • Suitable for research of celiac disease (CeD)
  • Shows no cytotoxic activity in Huh7 and CaCo2 cells
  • Inhibits TG2 in small intestinal mucosa both in vitro and in vivo

Catalog No. 50-003-86127


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