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Medchemexpress LLC 2-hydroxybutyric acid (α-hydroxybutyric acid) | 600-15-7 | 98.0% | 104.10 | 1 G
SDP

Supplier:  Medchemexpress LLC HY1133811G

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2-Hydroxybutyric acid (α-Hydroxybutyric acid) is an endogenous metabolite, converted from 2-Aminobutyric acid. It serves as a potential biomarker for type 2 diabetes and preeclampsia and has shown the ability to prevent acetaminophen (AP)-induced liver injury. This compound is synthesized as a coproduct of insulin resistance, contributing to insulin signaling impairment and mitochondrial overload.

  • Enhances cell viabilities and decreases AP-induced toxicities in BRL3A, AML12, and mice primary hepatocytes.
  • Prevents AP-induced liver injury in C57 mice.
  • Normalizes gene expressions related to inflammation response, oxidative stress, cell proliferation, and DNA damage.

Catalog No. 50-004-36719


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