2-Hydroxyisobutyric acid, 99% (dry wt.), water <2%

Description

CAS: 594-61-6 | C4H8O3 | 104.11 g/mol

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Solubility
Soluble in water, ether, alcohol, methanol and hot benzene.

Notes
Incompatible with oxidizing agents, bases and reducing agents.

Specifications

Chemical Identifiers

• CAS: 594-61-6
• Molecular Formula: C4H8O3
• Molecular Weight (g/mol): 104.11
• MDL Number: MFCD00004459
• InChI Key: BWLBGMIXKSTLSX-UHFFFAOYSA-N
• Synonym: 2-hydroxyisobutyric acid, 2-methyllactic acid, acetonic acid, 2-hydroxy-2-methylpropionic acid, alpha-hydroxyisobutyric acid, hydroxydimethylacetic acid, acetonate, propanoic acid, 2-hydroxy-2-methyl, alpha-hydroxyisobutanoic acid, 2-hydroxyisobutyricacid
• PubChem CID: 11671
• ChEBI: CHEBI:50129
• IUPAC Name: 2-hydroxy-2-methylpropanoic acid
• SMILES: CC(C)(O)C(O)=O

• Melting Point: 77°C to 80°C
• Density: 1.24
• Boiling Point: 114°C (12 mmHg)
• Quantity: 25 g
• Beilstein: 1744739
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water,ether,alcohol,methanol and hot benzene.
• Formula Weight: 104.11
• Percent Purity: 99%
• Assay: (dry wt.), water <2%
• Chemical Name or Material: 2-Hydroxyisobutyric acid

Safety and Handling

Hazard Category	H302-H315-H318-H335
Hazard Statement	GHS H Statement H318-H335-H315 Causes serious eye damage. May cause respiratory irritation. Causes skin irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c
EINECSNumber	209-848-8
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only