Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 g·mol⁻¹ | C4H8ClNS | 250 MG

Supplier:  Medchemexpress LLC 250MGHYW015798

2-Iminothiolane hydrochloride is a thiolating reagent (Traut's reagent) used to introduce sulfhydryl (-SH) groups into primary amines on proteins, peptides, and oligosaccharides for bioconjugation, labeling, and cross-linking. It reacts efficiently near neutral to slightly alkaline pH to form thiol-modified biomolecules while minimizing disruption of native structure.

• Reacts with primary amines at pH 7-10 to generate free sulfhydryl groups.
• Suitable for protein, peptide, and oligosaccharide modification for bioconjugation.
• High purity (≈99.9%) for reliable, reproducible results.
• Soluble in water (100 mg/mL) and DMSO (14.29 mg/mL) with ultrasonic or gentle warming as needed.
• Recommended storage sealed at 4°C; prepared solutions stable at -20°C (short term) or -80°C (long term) per datasheet.

Catalog No. 50-003-02842