2-Iodophenol, 98%

Description

CAS: 533-58-4 | C6H5IO | 220.01 g/mol

2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.

Solubility
Soluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 533-58-4
• Molecular Formula: C6H5IO
• Molecular Weight (g/mol): 220.01
• MDL Number: MFCD00013963
• InChI Key: KQDJTBPASNJQFQ-UHFFFAOYSA-N
• Synonym: o-iodophenol, phenol, 2-iodo, phenol, o-iodo, o-jodfenol, 2-jodfenol, phenol, iodo, o-jodfenol czech, 2-jodfenol czech, o-jodphenol, 2-iodanylphenol
• PubChem CID: 10784
• ChEBI: CHEBI:16706
• IUPAC Name: 2-iodophenol
• SMILES: OC1=CC=CC=C1I

• Melting Point: 39°C to 41°C
• Density: 1.947
• Boiling Point: 186°C to 187°C (160 mmHg)
• Flash Point: >110°C (230°F)
• Quantity: 5 g
• Beilstein: 1855300
• Sensitivity: Light sensitive
• Merck Index: 14,5035
• Solubility Information: Soluble in water.
• Formula Weight: 220.01
• Percent Purity: 98%
• Chemical Name or Material: 2-Iodophenol

Safety and Handling

Hazard Category	H302+H312+H332-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	208-569-9
RTECSNumber	SL5500000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only