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Medchemexpress LLC 2-Ketoglutaric acid potassium | 997-43-3 | 98.0% | 185.20 | 500 MG
Supplier: Medchemexpress LLC HYW013636C500MG
2-Ketoglutaric acid potassium, also known as Alpha-Ketoglutaric acid potassium, is an intermediate in the production of ATP or GTP in the Krebs cycle. It is a reversible and orally active inhibitor of tyrosinase, and also acts as a major carbon skeleton for nitrogen-assimilatory reactions.
- Suppresses abnormal intestinal permeability.
- Inhibits delocalization of tight junction proteins from intestinal cells.
- Reduces expression of TNFα in vitro and in vivo.
- Directly binds to TAK1 and inhibits TRAF6-TAK1 interaction.
- Alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis.
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