2-Mercaptoethanol, Electrophoresis Grade, 98+%

Description

CAS: 60-24-2 | C2H6OS | 78.13 g/mol

β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

Solubility
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.

Notes
Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 60-24-2
• Molecular Formula: C2H6OS
• Molecular Weight (g/mol): 78.13
• MDL Number: MFCD00004890
• InChI Key: DGVVWUTYPXICAM-UHFFFAOYSA-N
• Synonym: 2-mercaptoethanol, mercaptoethanol, thioglycol, beta-mercaptoethanol, ethanol, 2-mercapto, 2-thioethanol, 2-hydroxy-1-ethanethiol, thioethylene glycol, 2-hydroxyethanethiol, 2-hydroxyethyl mercaptan
• PubChem CID: 1567
• ChEBI: CHEBI:41218
• SMILES: OCCS

• Melting Point: -100°C
• Color: Colorless
• Density: 1.114 g/mL
• Boiling Point: 156°C to 158°C
• Flash Point: 73°C (163°F)
• Odor: Unpleasant
• Linear Formula: HSCH₂CH₂OH
• Quantity: 250 g
• UN Number: UN2966
• Beilstein: 773648
• Sensitivity: Air sensitive; Hygroscopic
• Merck Index: 14,5869
• Solubility Information: Fully miscible in water. Soluble in alcohol,ether,benzene,and other organic solvents.
• IUPAC Name: 2-sulfanylethanol
• Formula Weight: 78.13
• Percent Purity: ≥98%
• Grade: Electrophoresis
• Physical Form: Liquid
• Chemical Name or Material: 2-Mercaptoethanol

Safety and Handling

Hazard Category	H227-H301+H331-H310-H315-H317-H318-H373
Hazard Statement	GHS H Statement H301-H310-H318-H227-H315-H317-H335 Toxic if swallowed. Fatal in contact with skin. Causes serious eye damage. Combustible liquid. Causes skin irritation. May cause an allergic skin reaction. May cause respiratory irritation.
Precautionary Statement	P210-P235-P260-P262-P264b-P270-P271-P272-P280-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P311-P314-P330-P333+P313-P361-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packaging Group: II; Proper Shipping Name: THIOGLYCOL
EINECSNumber	200-464-6
RTECSNumber	KL5600000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only