2-Mercaptopyridine N-oxide, 99%

Description

CAS: 1121-31-9 | C5H5NOS | 127.161 g/mol

2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

Solubility
Soluble in tris-hydrochloric acid.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 1121-31-9
• Molecular Formula: C5H5NOS
• Molecular Weight (g/mol): 127.161
• MDL Number: MFCD00006196
• InChI Key: YBBJKCMMCRQZMA-UHFFFAOYSA-N
• Synonym: pyrithione, 2-mercaptopyridine n-oxide, 2-mercaptopyridine-n-oxide, 1-hydroxy-2-pyridinethione, omadine, 2-pyridinethiol, 1-oxide, 1-hydroxyl-1h-pyridine-2-thione, n-hydroxypyridine-2-thione, 1-hydroxy-2 1h-pyridinethione, 2-pyridinethiol 1-oxide
• PubChem CID: 1570
• ChEBI: CHEBI:36578
• IUPAC Name: 1-hydroxypyridine-2-thione
• SMILES: C1=CC(=S)N(C=C1)O

• Melting Point: 69°C to 72°C
• Quantity: 100 g
• Beilstein: 906983
• Sensitivity: Air and light sensitive
• Merck Index: 14,7994
• Solubility Information: Soluble in tris-hydrochloric acid.
• Formula Weight: 127.17
• Percent Purity: 99%
• Chemical Name or Material: 2-Mercaptopyridine N-oxide

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	214-329-4
RTECSNumber	UT8999000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only